Increasingly, Big Science organisations have areas with challenging environments – due to hazardous materials, or various types of radioactivity & radiation, or environmental constraints (such as temperature, pressure, magnetic field, vacuum) or at inaccessible locations like in space. Operations hence require specialized remote handling (RH) / robotics interventions. Solutions developed for the science community may also help to solve challenges in other markets such as manipulation of very large components, decommissioning, space, power generation, mining etc. The technical area includes RH mechanics, system design & engineering, tooling design, operations planning, radiation tolerant components & systems, electronics, simulation, control and testing environments.